15th SEC program!

The program outline for the 15th Annual Southeast Enzyme Conference 

Below is the program outline for the 15th SEC!

April 26, 2025

Location: GSU Student Center East Ballroom

All Talks include 5 min of Q&A

Program Schedule (Time: EDT)

7:30-8:30: Registration and Coffee Mixer

8:30-8:40:  Opening Remarks – Jack Dunkle (The University of Alabama)

Session 1

Discussion Leader: Melanie A. Higgins (University of Alabama)

8:40-9:00: Kendra Ireland (Emory University)

“Bond Formation Regioselectivity and Convergent Evolution: X-ray Crystallography Offers Unique Insights into Antioxidant-Biosynthetic Sulfoxide/Selenoxide Synthases”

9:00-9:20: Sarah Spigelmyer (Wake Forest University)

 “Probing Cysteine Desulfurase Interactions to Identify New Metabolic Targets for Antibiotic Development”

9:20 – 9:40: Wen Zhu (Florida State University)

“Conformational Dynamics Regulate the Accessibility of Ammonia in Human Asparagine Synthetase”

9:40-11:30: Poster Session 1

Session 2

Discussion Leader: Katherine W. Rush (Auburn University)

11:30 – 11:50: Bingnan Li (University of Georgia)

“Elucidating ligand interactions and small-molecule activation in the pyrrolnitrin biosynthetic enzyme PrnB”

11:50 – 12:10: Jessica Kugblenu (Georgia State University)

“On the Relevance of His⁴²¹ in Pseudomonas aeruginosa PAO1 D-2-Hydroxyglutarate Dehydrogenase”

12:10 – 12:30: Yi-Chien (Tiffany) Tang (Georgia Tech)

 “Elucidating the metabolism of lapidated serotonin by cytochrome P450 2U1 (CYP2U1) in nanodiscs”

12:30-1:30: Lunch Break

1:30-1:40: Group Photo

Session 3

Discussion Leader: Michael J. Reddish (Appalachian State University)

1:40 – 2:00: Matthew K. Thompson (University of Alabama)

 “Combating Fosfomycin Resistance in Gram-positive Pathogens”

2:00 – 2:20: Nirmal Saha (Georgia Tech)

 “Genome mining for the discovery of peptide halogenases and their biochemical characterization”

2:20 – 2:40: Daniel Tehrani (University of Georgia)

“Mechanistic And Structural Basis of Chondroitin Sulfate Backbone Polymer Synthesis”

2:40-4:30: Poster Session 2

Session 4

Discussion Leader:Jack Dunkle (The University of Alabama)

4:30 – 5:30: James Fraser (UCSF)

 “How to inhibit the SARS CoV 2 Macrodomain using protein structure and dynamics”

5:30 – 5:40: Concluding remarks and poster awards –Jack Dunkle

5:40-7:00: Social Networking mixer  (On-Site)

PDF versions of previous Southeast Enzyme Conference Abstract Books can be viewed by clicking here.